NAD 500mg Nasal Spray – 5mg/Spray

Nicotinamide Adenine Dinucleotide (NAD ) is a coenzyme present in every living cell, functioning as a critical electron carrier in oxidative phosphorylation and as a substrate for a broad class of enzymes including sirtuins, PARPs, and CD38. Biological systems that regulate DNA repair, gene expression, circadian rhythm, and cellular stress response. Hudson Science’s formulation delivers 500mg total NAD at 5mg per metered spray in a nasal delivery system; a non invasive administration route that bypasses the gastrointestinal degradation associated with oral NAD precursor compounds and avoids the injection site considerations of parenteral administration. The nasal delivery route is a pharmacokinetically meaningful distinction for NAD research. Oral NAD precursors such as NMN and NR require enzymatic conversion steps before contributing to intracellular NAD pools, the conversion efficiency of which varies across tissue types and individual metabolic conditions. Nasal administration of NAD itself bypasses these conversion pathways, delivering the intact coenzyme directly across the nasal mucosa into systemic circulation. Additionally the nasal route provides proximity to the olfactory epithelium and potential access to the central nervous system via the olfactory nerve pathway. A delivery characteristic that has generated specific research interest in studies examining NAD bioavailability in brain tissue and neurological applications of NAD repletion. NAD research has expanded dramatically over the past decade, driven by the discovery of its central role in sirtuin enzyme activation and its well documented decline with age across multiple tissue types. Current research literature encompasses mitochondrial function and biogenesis, DNA damage repair through PARP enzyme activity, neurodegeneration and neuroprotection, metabolic syndrome, and cellular senescence. A research scope that has made NAD one of the most broadly investigated compounds in contemporary longevity and metabolic science. The nasal spray format positions this formulation as a distinct research tool from injectable NAD and oral precursor compounds, supporting comparative bioavailability and delivery route studies within the NAD research family. Hudson Science formulations are stocked by Canada Steroid Depot following the same rigorous third party lab verification process applied to every product in our range. Each batch is tested for concentration accuracy and purity before being made available, with COA documentation available on request. CSD’s sourcing standards apply uniformly across all manufacturers we carry, and Hudson Science’s NAD nasal spray meets those standards consistently. All orders ship discreetly across Canada in plain, unmarked packaging with no identifying information on the exterior. Store at 2–8°C away from direct light. Do not freeze. Keep upright. Intended for research purposes only. Commonly researched alongside MOTS-C and Epithalon in comparative longevity and cellular energy metabolism studies. Browse CSD’s full peptide and research compound range for complete sourcing.