Glutathione 500mg Nasal Spray – 5mg/Spray

Glutathione (GSH) is a tripeptide composed of glutamate, cysteine, and glycine; the most abundant endogenous antioxidant in human cells and a central component of the body’s primary oxidative stress defense system. Hudson Science’s formulation delivers 500mg total glutathione at 5mg per metered spray in a nasal delivery system. A non invasive administration route that addresses one of the most fundamental challenges in glutathione research: delivering intact glutathione to systemic circulation and target tissues in bioavailable form. The delivery route is the defining research characteristic of this formulation. Oral glutathione supplementation faces significant bioavailability limitations; the tripeptide is substantially degraded by gastrointestinal enzymes before absorption, with much of the administered dose hydrolyzed into its constituent amino acids rather than reaching systemic circulation as intact GSH. Intravenous administration bypasses this limitation but introduces parenteral administration considerations. Nasal delivery occupies a distinct position between the two, bypassing gastrointestinal degradation while remaining non invasive, with the nasal mucosa providing a permeable absorption surface for intact peptide delivery into systemic circulation. The proximity to the olfactory epithelium additionally supports research into intranasal glutathione delivery to the central nervous system, an area of growing interest given glutathione’s role in neuronal oxidative stress defense and its documented depletion in neurodegenerative research models. Glutathione’s biological roles extend well beyond simple antioxidant activity. As the primary substrate for glutathione S-transferase enzymes, GSH is central to phase II detoxification of xenobiotics and reactive metabolites in hepatic tissue. It maintains the redox state of protein thiol groups, supports immune cell proliferation and function, and serves as a cofactor for glutathione peroxidase enzymes that neutralize hydrogen peroxide and lipid peroxides, a breadth of biological function that has made glutathione one of the most extensively studied molecules in biochemistry, with research literature spanning oxidative stress, liver function, immune regulation, neurodegeneration, and cellular senescence. Hudson Science formulations are stocked by Canada Steroid Depot following the same rigorous third party lab verification process applied to every product in our range. Each batch is tested for concentration accuracy and purity before being made available, with COA documentation available on request. CSD’s sourcing standards apply uniformly across all manufacturers we carry, and Hudson Science’s Glutathione nasal spray meets those standards consistently. All orders ship discreetly across Canada in plain, unmarked packaging with no identifying information on the exterior. Store at 2–8°C away from direct light. Do not freeze. Keep upright. Intended for research purposes only. Commonly researched alongside NAD and other antioxidant compounds in oxidative stress, detoxification, and cellular defense studies. Browse CSD’s full peptide and research compound range for complete sourcing.